Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.72 |
| ▸ | METAP2 | P50579 | 1/20 | 0.72 |
| ▸ | METAP1 | P53582 | 1/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.62 |
| ▸ | ACR | P10323 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199491 | 0.85 | LMNA (0.78) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| Benzoxiquine SCHEMBL360626 | 0.84 | LMNA (1.00) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| Benzoxiquine SCHEMBL29729484 | 0.84 | LMNA (1.00) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| Benzoxiquine SCHEMBL30599448 | 0.84 | LMNA (1.00) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| SCHEMBL11074045 | 0.82 | LMNA (0.65) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| SCHEMBL28178582 | 0.81 | LMNA (0.72) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| SCHEMBL13674015 | 0.81 | LMNA (0.72) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| SCHEMBL13396893 | 0.81 | LMNA (0.72) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| SCHEMBL13396854 | 0.81 | LMNA (0.67) | LMNAMETAP2METAP1HDAC6ALDH1A1 | |
| SCHEMBL19084337 | 0.80 | ESR1 (0.62) | LMNAALDH1A1L3MBTL1MAPTPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4530931-A | 8-Quinoline carbanilates for the inhibition of lipolysis | USV PHARMACEUTICAL CORP. (US) | 1985-07-23 | — | — | US | disclosed |