⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498793 | 0.78 | — | — | |
| Urea SCHEMBL28173262 | 0.75 | — | — | |
| SCHEMBL7587252 | 0.75 | LMNA (0.35) | — | |
| SCHEMBL11330802 | 0.75 | LMNA (0.35) | — | |
| SCHEMBL1416273 | 0.74 | — | — | |
| SCHEMBL1661014 | 0.73 | — | — | |
| SCHEMBL293056 | 0.73 | — | — | |
| SCHEMBL5459979 | 0.73 | — | — | |
| SCHEMBL1863499 | 0.73 | — | — | |
| SCHEMBL291978 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084173-A | 1-azabicyclo [3,2,0] hept-2-ene\"-2-carboxylic acid derivative and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-23 | — | — | CN | claimed |
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | claimed |
| US-20120165351-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2012-06-28 | — | — | US | disclosed |
| US-8153643-B2 | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2012-04-10 | — | — | US | disclosed |
| EP-1802591-B1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2012-01-11 | — | — | EP | disclosed |
| US-7973164-B2 | Quinoline derivatives | ASTRAZENECA AB (SE) | 2011-07-05 | — | — | US | disclosed |
| EP-2165830-B1 | Lithographic printing plate precursor and printing method using the same | FUJIFILM CORP (JP) | 2011-03-16 | — | — | EP | disclosed |
| US-7893063-B2 | 2,4,6-trisubstituted pyrimidines as phosphotidylinositol (PI) 3-kinase inhibitors and their use in the treatment of cancer | ASTRAZENECA AB (SE) | 2011-02-22 | — | — | US | disclosed |
| US-7888379-B2 | N-[5-(5-formyl-2-thienyl)-4-methyl-1,3-thiazol-2-yl]acetamide; autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer | MERCK SERONO SA (CH) | 2011-02-15 | — | — | US | disclosed |
| EP-2109612-B1 | 5,6,7,8-TETRAHYDROPTERIDINE DERIVATIVES AS HSP90 INHIBITORS | ASTRAZENECA AB (SE) | 2010-11-10 | — | — | EP | disclosed |
| US-7799781-B2 | 5,6,7,8-tetrahydropteridine derivatives as HSP90 inhibitors | ASTRAZENECA AB (SE) | 2010-09-21 | — | — | US | disclosed |
| EP-1439834-A1 | OXINDOLE HYDRAZIDE MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-07-28 | — | — | EP | disclosed |
| WO-2004012656-A2 | THIOPHENE AND FURAN DERIVATIVES AS PROSTAGLANDIN AGONISTS AND USE THEREOF | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2004-02-12 | — | — | WO | disclosed |
| WO-2003037328-A1 | OXINDOLE HYDRAZIDE MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2003-05-08 | — | — | WO | disclosed |
| US-5371226-A | Hypotensive agents | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-12-06 | — | — | US | disclosed |
| US-5328818-A | Support with color couplers in emulsions in multilayer element | FUJI PHOTO FILM CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| CN-1084173-A | 1-azabicyclo [3,2,0] hept-2-ene\"-2-carboxylic acid derivative and preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-03-23 | — | — | CN | disclosed |
| WO-1993023402-A1 | 3-AZETIDINYLTHIO-CARBAPENEME DERIVATIVES, THEIR PREPARATION AND USE AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-25 | — | — | WO | disclosed |
| EP-0561252-A1 | 2-Oxoquinoline derivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-09-22 | — | — | EP | disclosed |
| EP-0319999-A2 | Silver halide photographic materials | Fuji Photo Film Co., Ltd. (JP) | 1989-06-14 | — | — | EP | disclosed |