Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 11/20 | 0.46 |
| ▸ | CNR1 | P21554 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843172 | 0.86 | CNR2 (0.57) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL10993811 | 0.85 | CNR2 (0.50) | CNR2CNR1MEN1KMT2AMAPT | |
| SCHEMBL10996675 | 0.82 | CNR2 (0.56) | MCL1CNR2ALDH1A1RAB9AMEN1 | |
| SCHEMBL10993468 | 0.81 | CNR2 (0.47) | CNR2ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL11160417 | 0.80 | ACMSD (0.49) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL10989639 | 0.79 | CNR2 (0.47) | MCL1CNR2CNR1KDM4EALDH1A1 | |
| SCHEMBL10994806 | 0.79 | CYP3A4 (0.46) | CNR2KDM4EALDH1A1RAB9AMEN1 | |
| SCHEMBL10998292 | 0.77 | CNR2 (0.46) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL10992081 | 0.77 | CNR2 (0.50) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL10998091 | 0.76 | CNR2 (0.40) | CNR2CNR1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003144-B1 | 4-PYRIDONE-3-CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THEIR PREPARATION, THEIR APPLICATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-08-05 | — | — | EP | claimed |
| US-4549022-A | ANTIBACTERIAL AGENT; STIMULANT ON CENTRAL NERVOUS SYSTEM | HOFFMANN-LA ROCHE INC. (US) | 1985-10-22 | — | — | US | disclosed |
| US-4521535-A | ANTIBACTERIAL AGENTS; STIMULANTS FOR CENTRAL NERVOUS SYSTEM | HOFFMANN-LA ROCHE INC. (US) | 1985-06-04 | — | — | US | disclosed |
| EP-0003144-B1 | 4-PYRIDONE-3-CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESSES FOR THEIR PREPARATION, THEIR APPLICATION | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-08-05 | — | — | EP | disclosed |
| EP-0003144-A2 | 4-Pyridone-3-carboxylic acid derivatives, pharmaceutical compositions containing them, processes for their preparation, their application | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-25 | — | — | EP | disclosed |