Alcohol

Alcohol

SCHEMBL10990969

CCCCCCC(C)(O)C=Cc1ccccc1.CCO

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.47
MBOAT4 Q96T53 1/20 0.44
CYP2C19 P33261 1/20 0.41
HDAC3 O15379 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
TUBB4A P04350 2/20 0.40
TUBB P07437 2/20 0.40
TUBA3C P0DPH7 2/20 0.40
TUBA1B P68363 2/20 0.40
TUBA4A P68366 2/20 0.40
TUBB4B P68371 2/20 0.40
TUBB3 Q13509 2/20 0.40
TUBB2A Q13885 2/20 0.40
TUBB8 Q3ZCM7 2/20 0.40
TUBA3E Q6PEY2 2/20 0.40
TUBA1A Q71U36 2/20 0.40
TUBA1C Q9BQE3 2/20 0.40
TUBB6 Q9BUF5 2/20 0.40
TUBB2B Q9BVA1 2/20 0.40
TUBB1 Q9H4B7 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28096624 0.95 EGFR (0.47) EGFRMBOAT4CYP2C19HDAC3TDP1
SCHEMBL7101868 0.91 CYP2C19 (0.45) EGFRMBOAT4CYP2C19HDAC3TDP1
SCHEMBL7101867 0.91 CYP2C19 (0.45) EGFRMBOAT4CYP2C19HDAC3TDP1
SCHEMBL28149239 0.84 CYP2C19 (0.47) EGFRCYP2C19HDAC3TDP1NPC1
SCHEMBL23406262 0.83 EGFR (0.50) EGFRCYP2C19HDAC3TDP1TUBB4A
SCHEMBL6858892 0.81 EGFR (0.48) EGFRCYP2C19HDAC3TDP1TUBB4A
SCHEMBL2787746 0.81 EGFR (0.48) EGFRCYP2C19HDAC3TDP1TUBB4A
SCHEMBL2785211 0.79 EGFR (0.45) EGFRCYP2C19HDAC3TDP1TUBB4A
SCHEMBL7127915 0.77 CYP2C19 (0.50) EGFRCYP2C19HDAC3TDP1NPC1
SCHEMBL7127921 0.77 CYP2C19 (0.50) EGFRCYP2C19HDAC3TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4519909-A HOMOGENEOUS, THREE-DIMENSIONAL POLYMER STRUCTURE AKZONA INCORPORATED (US) 1985-05-28 US disclosed