Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101868 | 1.00 | CYP2C19 (0.45) | CYP2C19EGFRHDAC3NPC1L3MBTL1 | |
| SCHEMBL28096624 | 0.95 | EGFR (0.47) | CYP2C19EGFRHDAC3NPC1L3MBTL1 | |
| Alcohol SCHEMBL10990969 | 0.91 | EGFR (0.47) | CYP2C19EGFRHDAC3NPC1L3MBTL1 | |
| SCHEMBL28149239 | 0.89 | CYP2C19 (0.47) | CYP2C19EGFRHDAC3NPC1L3MBTL1 | |
| SCHEMBL7127915 | 0.82 | CYP2C19 (0.50) | CYP2C19EGFRHDAC3NPC1L3MBTL1 | |
| SCHEMBL7127921 | 0.82 | CYP2C19 (0.50) | CYP2C19EGFRHDAC3NPC1L3MBTL1 | |
| SCHEMBL19130587 | 0.82 | CYP2C19 (0.50) | CYP2C19EGFRHDAC3NPC1L3MBTL1 | |
| SCHEMBL2813638 | 0.80 | CYP2C19 (0.44) | CYP2C19EGFRHDAC3NPC1L3MBTL1 | |
| SCHEMBL16552541 | 0.78 | CYP2C19 (0.50) | CYP2C19EGFRHDAC3NPC1L3MBTL1 | |
| SCHEMBL23406262 | 0.78 | EGFR (0.50) | CYP2C19EGFRHDAC3NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846678-B1 | Process for the preparation of N-hydrocarbyl-substituted amides | LUBRIZOL CORP (US) | 2003-09-10 | — | — | EP | disclosed |
| EP-0847988-B1 | Process for the preparation of N-hydrocarbyl-substituted amides | LUBRIZOL CORP (US) | 2003-09-03 | — | — | EP | disclosed |
| US-5811580-A | TREATING A NITRILE WITH AN ALKYLATING AGENT IN THE PRESENCE OF AN ACIDIFIED CLAY YIELDS ALKYL AMIDES | THE LUBRIZOL CORPORATION (US) | 1998-09-22 | — | — | US | disclosed |
| EP-0847988-A1 | Process for the preparation of N-hydrocarbyl-substituted amides | The Lubrizol Corporation (US) | 1998-06-17 | — | — | EP | disclosed |
| EP-0846678-A1 | Process for the preparation of N-hydrocarbyl-substituted amides | The Lubrizol Corporation (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5712413-A | Process for the preparation of N-hydrocarbyl-substituted amides such as tert-butylacrylamide via the Ritter reaction using solid heteropolyacid catalysts | THE LUBRIZOL CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |