Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.42 |
| ▸ | LDHB | P07195 | 3/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | JUN | P05412 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | BID | P55957 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.32 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855502 | 0.89 | LDHA (0.41) | LDHALDHBHCAR2PTPN1PTPN11 | |
| SCHEMBL10981379 | 0.82 | SMN1; SMN2 (0.39) | LDHALDHBHCAR2SMN1; SMN2PKM | |
| SCHEMBL5586968 | 0.80 | LDHA (0.49) | LDHALDHBHCAR2PTPN1PTPN11 | |
| Alcohol SCHEMBL29191762 | 0.79 | SMN1; SMN2 (0.43) | HCAR2PTPN1PTPN11SMN1; SMN2PKM | |
| SCHEMBL22418967 | 0.79 | LDHA (0.48) | LDHALDHBHCAR2PTPN1PTPN11 | |
| SCHEMBL14989236 | 0.79 | LDHA (0.48) | LDHALDHBHCAR2PTPN1PTPN11 | |
| SCHEMBL11936748 | 0.78 | SMN1; SMN2 (0.41) | HCAR2SMN1; SMN2PKMESR1MEN1 | |
| SCHEMBL27417437 | 0.78 | TAAR1 (0.39) | — | |
| SCHEMBL29927198 | 0.78 | HCAR2 (0.47) | LDHALDHBHCAR2SMN1; SMN2PKM | |
| SCHEMBL7855513 | 0.78 | HCAR2 (0.47) | LDHALDHBHCAR2SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551546-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-05 | — | — | US | disclosed |
| US-4429153-A | INSECTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-01-31 | — | — | US | disclosed |
| EP-0031199-B1 | SUBSTITUTED BENZYL ESTERS OF CYCLOPROPANE CARBOXYLIC ACIDS AND THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND METHODS OF COMBATING INSECT PESTS THEREWITH, AND SUBSTITUTED BENZYL ALCOHOLS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-12-14 | — | — | EP | disclosed |
| US-4405640-A | Substituted fluorobenzyl cyclopropane carboxylates useful as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-09-20 | — | — | US | disclosed |
| EP-0060617-A1 | Fluorobenzyl cyclopropane carboxylates, their preparation, compositions and use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
| EP-0031199-A1 | Substituted benzyl esters of cyclopropane carboxylic acids and their preparation, compositions containing them and methods of combating insect pests therewith, and substituted benzyl alcohols | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-01 | — | — | EP | disclosed |