Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994663 | 0.87 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL10990185 | 0.81 | POLB (0.41) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL11369651 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL11363847 | 0.78 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1MAPTHPGD | |
| SCHEMBL11367667 | 0.72 | POLB (0.46) | ALDH1A1MAPTTP53HPGDMAPK1 | |
| SCHEMBL11361250 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL22082618 | 0.72 | MEN1 (0.48) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL11368074 | 0.72 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL11367971 | 0.71 | POLB (0.45) | ALDH1A1MAPTHTTTP53HPGD | |
| SCHEMBL11377070 | 0.71 | POLB (0.45) | ALDH1A1MAPTHTTTP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4561880-A | 1H[1,2,4]-Triazolo[1,2-a]pyridazine-1,3-diones useful as herbicides | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1985-12-31 | — | — | US | disclosed |
| EP-0104484-A1 | A heterocyclic compound and its use as herbicide | Nippon Kayaku Kabushiki Kaisha (JP) | 1984-04-04 | — | — | EP | disclosed |