Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.56 |
| ▸ | CTSA | P10619 | 2/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30239579 | 0.87 | EGLN1 (0.62) | EGLN1CTSAEGLN3ALDH1A1 | |
| SCHEMBL1921425 | 0.87 | EGLN1 (0.62) | EGLN1CTSAEGLN3ALDH1A1 | |
| SCHEMBL1921935 | 0.87 | EGLN1 (0.70) | EGLN1CTSAEGLN3 | |
| SCHEMBL31226250 | 0.87 | EGLN1 (0.68) | EGLN1CTSAEGLN3SMN1; SMN2 | |
| SCHEMBL1921938 | 0.87 | EGLN1 (0.68) | EGLN1CTSAEGLN3SMN1; SMN2 | |
| SCHEMBL4371717 | 0.86 | EGLN1 (0.61) | EGLN1CTSAEGLN3 | |
| SCHEMBL24405062 | 0.83 | CTSA (0.50) | EGLN1CTSAKDM4CEGLN3 | |
| SCHEMBL12979255 | 0.83 | EGLN1 (0.61) | EGLN1CTSAEGLN3KDM4EALDH1A1 | |
| SCHEMBL1923031 | 0.83 | EGLN1 (0.61) | EGLN1CTSAKDM4CEGLN3ALDH1A1 | |
| SCHEMBL1921440 | 0.83 | EGLN1 (0.70) | EGLN1USP30EGLN3FTOEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555520-A | 2-Pyridylcarboxamides which inhibit arachidonic acid release | E. R. SQUIBB & SONS, INC. (US) | 1985-11-26 | — | — | US | disclosed |