SCHEMBL10992811

SCHEMBL10992811

CCCC(=O)Nc1cc(=O)n(-c2ccccc2)[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.45
TP53 P04637 1/20 0.45
MAPT P10636 4/20 0.44
ALDH1A1 P00352 3/20 0.44
LMNA P02545 2/20 0.44
HPGD P15428 1/20 0.44
POLB P06746 1/20 0.44
BLM P54132 1/20 0.44
ATM Q13315 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CTSA P10619 3/20 0.44
ALKBH5 Q6P6C2 2/20 0.43
TDP2 O95551 1/20 0.43
PAX8 Q06710 1/20 0.43
HKDC1 Q2TB90 1/20 0.43
TLR9 Q9NR96 1/20 0.43
ADORA1 P30542 1/20 0.43
MAPK1 P28482 1/20 0.42
MEN1 O00255 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11339863 0.92 TSHR (0.48) TSHRMAPTALDH1A1LMNAHPGD
SCHEMBL11863478 0.90 TSHR (0.53) TSHRSMN1; SMN2TP53MAPTALDH1A1
SCHEMBL11874577 0.90 SOAT1 (0.53) TSHRSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL11200731 0.90 SOAT1 (0.53) TSHRSMN1; SMN2ALDH1A1LMNAHPGD
SCHEMBL11326057 0.85 TSHR (0.50) TSHRSMN1; SMN2MAPTALDH1A1LMNA
SCHEMBL4591592 0.82 TSHR (0.51) TSHRSMN1; SMN2MAPTALDH1A1LMNA
SCHEMBL10915383 0.81 TSHR (0.52) TSHRSMN1; SMN2TP53MAPTALDH1A1
SCHEMBL11437662 0.81 TSHR (0.50) TSHRSMN1; SMN2MAPTALDH1A1LMNA
SCHEMBL7626297 0.80 TSHR (0.48) TSHRSMN1; SMN2MAPTALDH1A1LMNA
SCHEMBL11872764 0.80 TSHR (0.52) TSHRSMN1; SMN2MAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4522915-A 5-PYRAZOLONE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1985-06-11 US disclosed