SCHEMBL4591592

SCHEMBL4591592

O=C(Cc1ccccc1)Nc1cc(=O)n(-c2ccccc2)[nH]1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.51
ALDH1A1 P00352 8/20 0.49
MAPT P10636 5/20 0.49
HPGD P15428 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
HTT P42858 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
PKM P14618 1/20 0.49
XBP1 P17861 1/20 0.49
MAPK1 P28482 1/20 0.49
CCR6 P51684 1/20 0.49
EPHX2 P34913 1/20 0.47
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
KDM4E B2RXH2 4/20 0.46
POLB P06746 3/20 0.46
BLM P54132 2/20 0.46
USP2 O75604 1/20 0.46
ELOVL1 Q9BW60 1/20 0.46
MMP13 P45452 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11863478 0.86 TSHR (0.53) TSHRALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL11326057 0.86 TSHR (0.50) TSHRALDH1A1MAPTSMN1; SMN2HTT
SCHEMBL11589603 0.82 MEN1 (0.46) ALDH1A1MAPTHPGDSMN1; SMN2HTT
SCHEMBL10992811 0.82 TSHR (0.50) TSHRALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL11339863 0.80 TSHR (0.48) TSHRALDH1A1MAPTHPGDNPSR1
SCHEMBL10915383 0.80 TSHR (0.52) TSHRALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL7626297 0.78 TSHR (0.48) TSHRALDH1A1MAPTSMN1; SMN2CCR6
SCHEMBL11200731 0.78 SOAT1 (0.53) TSHRALDH1A1HPGDSMN1; SMN2NPSR1
SCHEMBL11874577 0.78 SOAT1 (0.53) TSHRALDH1A1HPGDSMN1; SMN2NPSR1
SCHEMBL11439427 0.77 ALDH1A1 (0.51) TSHRALDH1A1MAPTSMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5407777-A Diazo-type recording material comprising a 1-phenyl-3-pyrazolidone(phenidone) as an anti-oxidant FUJI PHOTO FILM CO., LTD. (JP) 1995-04-18 US claimed
US-5328796-A Diazo type recording material utilizing microencapsulated diazo compound, a coupler and a hydroxyphenylsulfone derivative FUJI PHOTO FILM CO., LTD. (JP) 1994-07-12 US claimed
US-4686547-A DIAZO COMPOUND, POLYVINYL ALCOHOL CONTAINING SILICON, SILICA FUJI PHOTO FILM CO., LTD. (JP) 1987-08-11 US claimed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
EP-1382385-B1 Microcapsule and process for manufacturing the same FUJIFILM CORP (JP) 2007-03-21 EP disclosed
US-7011922-B2 Thermal recording material FUJI PHOTO FILM CO., LTD. (JP) 2006-03-14 US disclosed
US-20050187102-A1 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2005-08-25 US disclosed
US-6919297-B2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 2005-07-19 US disclosed
US-6881810-B2 Microcapsule and process for manufacturing the same FUJI PHOTO FILM CO., LTD. (JP) 2005-04-19 US disclosed
EP-0992364-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 2005-01-12 EP disclosed
US-6815138-B2 COMPRISES MODIFIED POLYGLYCEROL LAYER AND DIAZO COUPLER; MICROCAPSULATION; IMPROVED COLOR DISPERSION, RADIATION TRANSPARENCY, AND GLOSSINESS FUJI PHOTO FILM CO., LTD. (JP) 2004-11-09 US disclosed
US-4722921-A MICROCAPSULES CONTAINING COLOR FORMER; THERMOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1988-02-02 US disclosed
US-4721700-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-01-26 US disclosed
US-4686547-A DIAZO COMPOUND, POLYVINYL ALCOHOL CONTAINING SILICON, SILICA FUJI PHOTO FILM CO., LTD. (JP) 1987-08-11 US disclosed
EP-0109838-B1 LIGHT AND HEAT-SENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1987-04-08 EP disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed
US-4598035-A LEUCO AND DISAZO DYES FUJI PHOTO FILM CO., LTD. (JP) 1986-07-01 US disclosed
US-4529681-A Microcapsules containing vinyl compound, photoinitiator and color forming compound FUJI PHOTO FILM CO., LTD. (JP) 1985-07-16 US disclosed
EP-0123224-A2 Heat sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1984-10-31 EP disclosed
EP-0109838-A2 Light and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1984-05-30 EP disclosed