Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 7/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10979024 | 0.93 | ADRB2 (0.50) | ADRB2ADRB1ADRB3CYP2D6NFKB1 | |
| SCHEMBL10977156 | 0.86 | ADRB2 (0.50) | ADRB2ADRB1ADRB3CYP2D6NFKB1 | |
| SCHEMBL10980025 | 0.84 | ADRB2 (0.43) | ADRB2ADRB1ADRB3CYP2D6NFKB1 | |
| SCHEMBL11033838 | 0.83 | ADRB2 (0.49) | ADRB2ADRB1ADRB3CYP2D6NFKB1 | |
| SCHEMBL10997074 | 0.81 | CASR (0.41) | ADRB2ADRB1ADRB3CYP2D6NFKB1 | |
| SCHEMBL9749811 | 0.80 | ADRB2 (0.47) | ADRB2ADRB1ADRB3CYP2D6NFKB1 | |
| SCHEMBL10976461 | 0.80 | ADRB2 (0.50) | ADRB2ADRB1ADRB3CYP2D6NFKB1 | |
| SCHEMBL11033834 | 0.79 | ADRB2 (0.49) | ADRB2ADRB1ADRB3CYP2D6NFKB1 | |
| SCHEMBL10984749 | 0.76 | ADRB2 (0.43) | ADRB2ADRB1ADRB3CYP2D6NFKB1 | |
| SCHEMBL9749810 | 0.76 | ADRB2 (0.41) | ADRB2ADRB1ADRB3CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4508725-A | BETA-ADRENERGIC BLOCKING AGENTS; GLAUCOMA TREATMENT | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1985-04-02 | — | — | US | disclosed |