Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 7/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.59 |
| ▸ | XDH | P47989 | 1/20 | 0.59 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.56 |
| ▸ | GABRP | O00591 | 4/20 | 0.55 |
| ▸ | GABRD | O14764 | 4/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.55 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.55 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.55 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.55 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.55 |
| ▸ | GABRE | P78334 | 4/20 | 0.55 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.55 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.55 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10991389 | 0.88 | CYP1A1 (0.60) | CYP1A1CYP1A2CYP1B1XDHCYSLTR1 | |
| SCHEMBL10995973 | 0.88 | CYSLTR1 (0.71) | CYP1A1CYP1A2CYP1B1XDHCYSLTR1 | |
| SCHEMBL10995137 | 0.88 | CYSLTR1 (0.63) | CYP1A1CYP1A2CYP1B1CYSLTR1GABRP | |
| Hydrochloric Acid SCHEMBL10993466 | 0.87 | CYSLTR1 (0.70) | CYP1A1CYP1A2CYP1B1XDHCYSLTR1 | |
| SCHEMBL10987004 | 0.87 | CYSLTR1 (0.56) | CYP1A1CYP1A2CYP1B1CYSLTR1TNKS | |
| SCHEMBL10987884 | 0.84 | CYSLTR1 (0.62) | CYP1A1CYP1A2CYP1B1CYSLTR1GABRP | |
| SCHEMBL10994082 | 0.83 | TNKS (0.58) | CYSLTR1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10988521 | 0.82 | CYP1A1 (0.63) | CYP1A1CYP1A2CYP1B1CYSLTR1GABRP | |
| SCHEMBL10992543 | 0.81 | TP53 (0.54) | CYP1A1CYP1A2CYP1B1CYSLTR1PRKDC | |
| SCHEMBL2149390 | 0.80 | CYP1A2 (0.64) | CYP1A1CYP1A2CYP1B1CYSLTR1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525356-A | UROGENITAL DISORDERS | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| EP-0108986-A1 | N-substituted flavone-8-carboxamides | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1984-05-23 | — | — | EP | disclosed |