Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 9/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10991389 | 0.89 | CYP1A1 (0.60) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP19A1 | |
| SCHEMBL1516397 | 0.88 | CYSLTR1 (0.78) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP19A1 | |
| SCHEMBL10987004 | 0.88 | CYSLTR1 (0.56) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP19A1 | |
| SCHEMBL10993460 | 0.88 | CYP1A1 (0.59) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP19A1 | |
| SCHEMBL10988521 | 0.88 | CYP1A1 (0.63) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL10995142 | 0.87 | CYSLTR1 (0.76) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP19A1 | |
| SCHEMBL10992543 | 0.87 | TP53 (0.54) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP19A1 | |
| SCHEMBL10823330 | 0.86 | CYSLTR1 (0.63) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP19A1 | |
| SCHEMBL10987884 | 0.84 | CYSLTR1 (0.62) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP3A4 | |
| SCHEMBL2149390 | 0.83 | CYP1A2 (0.64) | CYSLTR1CYP1B1CYP1A2CYP1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525356-A | UROGENITAL DISORDERS | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| EP-0108986-A1 | N-substituted flavone-8-carboxamides | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1984-05-23 | — | — | EP | disclosed |