Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.56 |
| ▸ | RARB | P10826 | 6/20 | 0.56 |
| ▸ | RARG | P13631 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | RXRA | P19793 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | RXRB | P28702 | 3/20 | 0.47 |
| ▸ | RXRG | P48443 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993621 | 1.00 | RARA (0.56) | RARARARBRARGCYP1A2ALDH1A1 | |
| SCHEMBL10993615 | 1.00 | RARA (0.56) | RARARARBRARGCYP1A2ALDH1A1 | |
| SCHEMBL10990211 | 0.90 | RARA (0.65) | RARARARBRARGCYP1A2ALDH1A1 | |
| SCHEMBL9067692 | 0.90 | RARA (0.65) | RARARARBRARGCYP1A2ALDH1A1 | |
| SCHEMBL9067691 | 0.90 | RARA (0.65) | RARARARBRARGCYP1A2ALDH1A1 | |
| SCHEMBL10987204 | 0.90 | RARA (0.54) | RARARARBRARGCYP1A2ALDH1A1 | |
| SCHEMBL10987198 | 0.90 | RARA (0.54) | RARARARBRARGCYP1A2ALDH1A1 | |
| SCHEMBL10987202 | 0.90 | RARA (0.54) | RARARARBRARGCYP1A2ALDH1A1 | |
| SCHEMBL10991291 | 0.88 | RARA (0.54) | RARARARBRARGCYP1A2ALDH1A1 | |
| SCHEMBL10991283 | 0.88 | RARA (0.54) | RARARARBRARGCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518609-A | ANTITUMOR, SKIN DISORDERS | SRI INTERNATIONAL (US) | 1985-05-21 | — | — | US | disclosed |
| US-4456618-A | ANTITUMOR AGENTS, TREATMENT OF SKIN DISORDERS | SRI INTERNATIONAL (US) | 1984-06-26 | — | — | US | disclosed |