Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 7/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | GCGR | P47871 | 4/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | MATK | P42679 | 1/20 | 0.52 |
| ▸ | FRK | P42685 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.52 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6469124 | 0.81 | MAPK13 (0.68) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL11371516 | 0.79 | MAPK14 (0.52) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL11191080 | 0.79 | KDM4E (0.60) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL10995633 | 0.77 | MAPK14 (0.56) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL10988033 | 0.77 | GCGR (0.56) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL10993607 | 0.76 | NOX1 (0.59) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL8423174 | 0.76 | MAPK13 (0.61) | MAPK13MAPK12MAPK11MAPK14GCGR | |
| SCHEMBL20504148 | 0.76 | MAPK13 (0.67) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL11462878 | 0.76 | KDM4E (0.55) | MAPK13MAPK12MAPK11MAPK14ALOX5 | |
| SCHEMBL1131081 | 0.76 | MAPK13 (0.67) | MAPK13MAPK12MAPK11MAPK14ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503065-A | ANTIARTHRITIC, ANALGESIC | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-05 | — | — | US | disclosed |