SCHEMBL1099557

SCHEMBL1099557

c1ccc2c(c1)-c1cccc3c1C2COC3

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.34
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
HTR1A P08908 1/20 0.31
DRD2 P14416 1/20 0.31
NOTUM Q6P988 1/20 0.30
FGFR1 P11362 1/20 0.30
FGFR2 P21802 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1087686 0.70 GID4 (0.43) HTR1ADRD2
SCHEMBL1099491 0.70 HTR2A (0.35) HTR2AHTR1ADRD2FGFR1FGFR2
SCHEMBL1099172 0.69 HTR2A (0.66) HTR2ADRD2
SCHEMBL12998420 0.65 HTR2A (0.57) HTR2A
SCHEMBL3253163 0.65 HTR2A (0.57) HTR2A
SCHEMBL25180633 0.64 HTR2A (0.34) HTR2AMAOAMAOBNOTUM
SCHEMBL15145778 0.64 HTR2A (0.43) HTR2ANOTUM
SCHEMBL19829938 0.64 HTR2A (0.43) HTR2ANOTUM
SCHEMBL19829945 0.64 HTR2A (0.43) HTR2ANOTUM
SCHEMBL3554635 0.64 HTR2A (0.34) HTR2AMAOAMAOBNOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153276-B2 Polymer compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-10 US disclosed
US-8153276-B2 Polymer compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-10 US disclosed
US-20100066237-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
US-20100066237-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
US-20090174326-A1 POLYMER MATERIAL AND POLYMER LIGHT-EMITTING DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-09 US disclosed
US-20090174326-A1 POLYMER MATERIAL AND POLYMER LIGHT-EMITTING DEVICE USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-09 US disclosed