SCHEMBL109960

SCHEMBL109960

CC(C)C(=O)C(=O)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.40
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC7A5 Q01650 1/20 0.32
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Oxoisovalerate SCHEMBL1462512 0.79 TP53 (0.41) TSHRTP53SLC7A5FFAR3LCK
SCHEMBL10308365 0.79 TSHR (0.42) TSHRTP53ALDH1A1LMNATDP1
2-Oxoisovalerate SCHEMBL30552298 0.79
SCHEMBL6992690 0.79
SCHEMBL107888 0.79
SCHEMBL10308369 0.79 TSHR (0.42) TSHRTP53ALDH1A1LMNATDP1
2-Oxoisovalerate SCHEMBL42329 0.79
SCHEMBL2214959 0.76
2-Oxoisovalerate SCHEMBL6846904 0.76
SCHEMBL642131 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463374-A2 Isolated alcohol dehydrogenase enzymes and uses thereof Bio Architecture Lab, Inc. (US) 2012-06-13 EP claimed
EP-2195440-A2 BIOFUEL PRODUCTION Bio Architecture Lab, Inc. (US) 2010-06-16 EP claimed
US-20090155873-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-18 US claimed
US-20090139134-A1 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-06-04 US claimed
WO-2009046375-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
WO-2009046370-A2 BIOFUEL PRODUCTION BIO ARCHITECTURE LAB, INC. (US) 2009-04-09 WO claimed
US-7285688-B2 Proton type β zeolite, preparation method thereof and process for preparing phenol compound using the same UBE INDUSTRIES, LTD. (JP) 2007-10-23 US claimed
US-5618982-A SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES RHONE-POULENC CHIMIE (FR) 1997-04-08 US claimed
US-4084970-A Organic volume phase holographic recording media using sucrose benzoate RCA CORPORATION (US) 1978-04-18 US claimed
EP-3230463-B2 RAPID PRETREATMENT APALTA PATENTS OUE (EE) 2025-07-16 EP disclosed
US-20240425893-A1 RAPID PRETREATMENT Apalta Patents OÜ (EE) 2024-12-26 US disclosed
WO-2024234728-A1 6'-CYANO-MODIFIED LOCKED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID POLYMER 中国人民解放军军事科学院军事医学研究院 2024-11-21 WO disclosed
US-12054761-B2 Rapid pretreatment Apalta Patents OÜ (EE) 2024-08-06 US disclosed
US-12037405-B2 Anti-CD70 antibody drug conjugates AMBRX, INC. 2024-07-16 US disclosed
US-4608423-A Linear addition polyester copolymers SCM CORPORATION (US) 1986-08-26 US disclosed
US-4547323-A Synthesis of 2,2-dimethyl-4-methyleneglutaric acid and derivatives SCM CORPORATION (US) 1985-10-15 US disclosed
US-4526945-A Copolymerizing methacrylic monomer or methacrylic and ethylenic monomers in the presence of free radical catalyst and cobalt glyoxime catalyst SCM CORPORATION (US) 1985-07-02 US disclosed
US-4084970-A Organic volume phase holographic recording media using sucrose benzoate RCA CORPORATION (US) 1978-04-18 US disclosed
US-3956317-A HIGH HEAT DISTORTION POINT CIBA-GEIGY AG (CH) 1976-05-11 US disclosed
US-3951663-A Organic volume phase holographic recording media comprising an α di-ketone RCA CORPORATION (US) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037405-B2 Anti-CD70 antibody drug conjugates CD74, CD63, CD47 TSHR 3236/4885TP53 559/4885ALDH1A1 868/4885
US-20090139134-A1 BIOFUEL PRODUCTION MGAM, DCXR, MANBA TSHR 3426/4885TP53 3946/4885ALDH1A1 753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.