⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109960 | 0.76 | TSHR (0.41) | — | |
| SCHEMBL1913457 | 0.76 | — | — | |
| SCHEMBL20315006 | 0.73 | — | — | |
| SCHEMBL928 | 0.72 | — | — | |
| SCHEMBL1091792 | 0.71 | — | — | |
| SCHEMBL7753987 | 0.71 | — | — | |
| SCHEMBL10926352 | 0.71 | — | — | |
| SCHEMBL29110230 | 0.69 | ALDH1A1 (0.50) | — | |
| SCHEMBL27543584 | 0.69 | TSHR (0.37) | — | |
| Fluoride SCHEMBL28229919 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4729513-A1 | A-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | Nanjing Chempion Biotechnology Co., Ltd. (CN) | 2026-04-22 | — | — | EP | disclosed |
| WO-2025001687-A1 | Α-KETO ACID AMIDE OR SUBSTITUTED OXALIC ACID AMIDE ESTER COMPOUND AND COMPOSITION THEREOF | 南京桦冠生物技术有限公司 | 2025-01-02 | — | — | WO | disclosed |
| CN-116554122-B | Alpha-keto acid amide or substituted oxalic acid amide ester compound and composition thereof | 南京桦冠生物技术有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116554122-A | Alpha-keto acid amide or substituted oxalic acid amide ester compound and composition thereof | 南京桦冠生物技术有限公司 | 2023-08-08 | — | — | CN | disclosed |
| US-20130197082-A1 | SHORT SYNTHESIS OF TOLTERODINE, INTERMEDIATES AND METABOLITES | LEK PHARMACEUTICALS D.D. (SI) | 2013-08-01 | — | — | US | disclosed |
| US-20130197082-A1 | SHORT SYNTHESIS OF TOLTERODINE, INTERMEDIATES AND METABOLITES | LEK PHARMACEUTICALS D.D. (SI) | 2013-08-01 | — | — | US | disclosed |
| EP-1960347-B1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | STERIX LTD (GB) | 2012-06-20 | — | — | EP | disclosed |
| US-8119627-B2 | Heterocyclic compounds as inhibitors of 17beta-HSD3 | STERIX LIMITED (GB) | 2012-02-21 | — | — | US | disclosed |
| US-20090023710-A1 | Compound | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
| EP-1960347-A2 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 3 (17BETA-HSD3) INHIBITORS | Sterix Limited (GB) | 2008-08-27 | — | — | EP | disclosed |
| US-4160100-A | OXAMIC ACID DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-07-03 | — | — | US | disclosed |
| US-4154961-A | Oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4128646-A | ANTIALLERGEN | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1978-12-05 | — | — | US | disclosed |
| US-4113880-A | ANTIALLERGENS | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4069343-A | OXAMIC ACID DERIVATIVES FOR THE PREVENTION OF IMMEDIATE TYPE HYPERSENSITIVITY REACTIONS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1978-01-17 | — | — | US | disclosed |
| US-4054657-A | Pyrimidinyl oxamic acids and esters, and compositions and methods for the suppression of allergic manifestations | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054661-A | Pyridyl oxamic acid derivatives and use in the prevention of allergic reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4054666-A | Compositions and methods of treating immediate hypersensitivity reactions with thiazolyl oxamic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-4036837-A | 2 Alkoxyoxamoyl-pyrazines | AMERICAN HOME PRODUCTS CORPORATION (US) | 1977-07-19 | — | — | US | disclosed |
| US-3966965-A | Oxamic acid derivatives for the prevention of immediate type hypersensitivity reactions | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |