Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584420 | 0.86 | ALDH1A1 (0.40) | CDK4CCND1CDK6PTPN11MAPT | |
| SCHEMBL10994290 | 0.83 | ALDH1A1 (0.41) | CDK4CCND1CDK6MAPTPOLB | |
| SCHEMBL10993928 | 0.81 | ALDH1A1 (0.39) | CDK4CCND1CDK6MAPTPOLB | |
| SCHEMBL3534676 | 0.80 | KMT2A (0.45) | CDK4CCND1CDK6MAPTPOLB | |
| SCHEMBL3291780 | 0.79 | MEN1 (0.44) | CDK4CCND1CDK6MAPTPOLB | |
| SCHEMBL9088257 | 0.73 | ALDH1A1 (0.42) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL9096765 | 0.73 | ALDH1A1 (0.41) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10655866 | 0.70 | CACNA2D1 (0.41) | — | |
| SCHEMBL11582977 | 0.69 | MAPT (0.43) | CDK4CCND1CDK6MAPTPOLB | |
| SCHEMBL3531188 | 0.69 | KMT2A (0.40) | CDK4CCND1CDK6MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556709-A | BACTERICIDES, FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-03 | — | — | US | disclosed |