⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1791577 | 1.00 | — | — | |
| SCHEMBL675940 | 1.00 | — | — | |
| SCHEMBL8187898 | 0.92 | — | — | |
| SCHEMBL771844 | 0.92 | — | — | |
| SCHEMBL9021017 | 0.89 | CYP1A2 (0.43) | — | |
| SCHEMBL1797706 | 0.78 | — | — | |
| SCHEMBL254419 | 0.69 | — | — | |
| SCHEMBL20384062 | 0.69 | CHRM2 (0.45) | — | |
| SCHEMBL2274269 | 0.69 | CHRM2 (0.45) | — | |
| SCHEMBL88667 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247596-A1 | PYRAZOLOTHIAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |
| CN-105555761-B | Biphenyl derivatives and process for preparing the same | 东亚ST 株式会社 | 2018-12-11 | — | — | CN | claimed |
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |
| US-9828339-B2 | Biphenyl derivatives and methods for preparing same | DONG-A ST CO., LTD (KR) | 2017-11-28 | — | — | US | claimed |
| US-20160176816-A1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG-A ST CO., LTD (KR) | 2016-06-23 | — | — | US | claimed |
| EP-3029026-A1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | Dong-A ST Co., Ltd. (KR) | 2016-06-08 | — | — | EP | claimed |
| CN-105555761-A | Novel biphenyl derivatives and process for preparing the same | DONG A ST CO LTD | 2016-05-04 | — | — | CN | claimed |
| EP-2183239-B1 | SULFONAMIDES AS TRPM8 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-08-22 | — | — | EP | claimed |
| US-20090264474-A1 | SULFONAMIDES AS TRPM8 MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-10-22 | — | — | US | claimed |
| EP-1246619-B1 | UROTENSIN-II RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-10-20 | — | — | EP | claimed |
| US-6544992-B1 | Carbonylamino pyrrolidine and piperidine derivatives | SMITHKLINE BEECHAM CORPORATION | 2003-04-08 | — | — | US | claimed |
| US-6514970-B1 | Pyrrolidines such as benzo(b)thiophene-2-carboxylic acid ((S)-1-((S)-1-(4-(1-benzyl-piperidin-4-yloxy)-3-chloro-benzyl)-pyrrolidin-3 -ylcarbamoyl)-3- methyl-butyl)-amide | SMITHKLINE BEECHAM CORPORATION | 2003-02-04 | — | — | US | claimed |
| US-6156752-A | Optically active 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC (US) | 2000-12-05 | — | — | US | claimed |
| EP-0899261-A1 | Optical active 1,4-dihydropyridine compounds as bradykinin antagonists | PFIZER INC. (US) | 1999-03-03 | — | — | EP | claimed |
| EP-0298177-B1 | PROCESS FOR PREPARING PRISTINAMYCINE IIB DERIVATIVES | RHONE-POULENC SANTE (FR) | 1992-04-15 | — | — | EP | claimed |
| EP-0252720-B1 | PRISTINAMYCIN PROCESS | MAY & BAKER LIMITED (GB) | 1991-09-18 | — | — | EP | claimed |
| EP-0248703-B1 | SYNERGISTINIC DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1991-05-15 | — | — | EP | claimed |
| US-4866172-A | Pristinamycin process | MAY & BAKER LIMITED (GB) | 1989-09-12 | — | — | US | claimed |
| EP-0191662-B1 | PRISTINAMYCINE IIB DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC SANTE (FR) | 1988-06-01 | — | — | EP | claimed |
| EP-0252720-A2 | Pristinamycin process | MAY & BAKER LIMITED (GB) | 1988-01-13 | — | — | EP | claimed |