⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099647 | 1.00 | — | — | |
| SCHEMBL1791577 | 1.00 | — | — | |
| SCHEMBL8187898 | 0.92 | — | — | |
| SCHEMBL771844 | 0.92 | — | — | |
| SCHEMBL9021017 | 0.89 | CYP1A2 (0.43) | — | |
| SCHEMBL1797706 | 0.78 | — | — | |
| SCHEMBL254419 | 0.69 | — | — | |
| SCHEMBL20384062 | 0.69 | CHRM2 (0.45) | — | |
| SCHEMBL2274269 | 0.69 | CHRM2 (0.45) | — | |
| SCHEMBL88667 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 387 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3849983-A1 | TRIAZOLO-PYRIMIDINE COMPOUNDS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD (CN) | 2021-07-21 | — | — | EP | claimed |
| EP-3837250-A1 | PYRAZINE COMPOUNDS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD (CN) | 2021-06-23 | — | — | EP | claimed |
| WO-2020052631-A1 | TRIAZOLO-PYRIMIDINE COMPOUNDS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2020-03-19 | — | — | WO | claimed |
| WO-2020035052-A1 | PYRAZINE COMPOUNDS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2020-02-20 | — | — | WO | claimed |
| US-20190275046-A1 | NOVEL COMBINATION | INTRA-CELLULAR THERAPIES, INC. (US) | 2019-09-12 | — | — | US | claimed |
| US-20190192519-A1 | NOVEL USES | INTRA-CELLULAR THERAPIES, INC. (US) | 2019-06-27 | — | — | US | claimed |
| US-20180177782-A9 | NOVEL USES | INTRA-CELLULAR THERAPIES, INC. (US) | 2018-06-28 | — | — | US | claimed |
| US-20180000825-A1 | NOVEL USES | INTRA-CELLULAR THERAPIES, INC. (US) | 2018-01-04 | — | — | US | claimed |
| CN-105175397-B | A kind of hydrobromic acid eletriptan synthetic method | 上海现代哈森（商丘）药业有限公司 | 2017-10-10 | — | — | CN | claimed |
| US-20170128453-A1 | NOVEL USES | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-05-11 | — | — | US | claimed |
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | claimed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | claimed |
| EP-0431955-A2 | 3-Amino-2-hydroxybornane derivatives, asymmetric Michael reaction using the same, and process for preparing optically active muscone utilizing Michael reaction | NIKKO KYODO CO., LTD. (JP) | 1991-06-12 | — | — | EP | claimed |
| EP-0362695-B1 | PYRROLOCARBAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1991-04-03 | — | — | EP | claimed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | claimed |
| US-4912107-A | Pyrrolocarbazole derivatives, compositions containing them, and methods for using them | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | claimed |
| CN-1035667-A | Indolocarbazole derivative and preparation method thereof and pharmaceutical composition | GOEDECKE AG (DE) | 1989-09-20 | — | — | CN | claimed |
| EP-0328000-A2 | Indolocarbazole derivatives, process for their preparation and medicines containing same | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1989-08-16 | — | — | EP | claimed |
| US-4248885-A | FOR GASTROINTESTINAL, UROGENITAL, RHEUMATIC, AND CARDIOVASCULAR DISEASE | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1981-02-03 | — | — | US | claimed |
| US-4186135-A | TREATMENT OF PSYCHOLOGICAL DISORDERS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1980-01-29 | — | — | US | claimed |