SCHEMBL10998271

SCHEMBL10998271

CC(=O)/N=C1\NC(=O)NC1=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
OGT O15294 1/20 0.36
USP2 O75604 1/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
MIF P14174 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10998274 1.00 KDM4E (0.36) KDM4EOGTUSP2MAPTRECQL
SCHEMBL11310397 0.77 KDM4E (0.36) KDM4EOGTUSP2MAPTRECQL
SCHEMBL11310393 0.77 KDM4E (0.36) KDM4EOGTUSP2MAPTRECQL
SCHEMBL10534653 0.62 MAPT (0.45) KDM4EOGTUSP2MAPTRECQL
SCHEMBL3279621 0.60 KDM4E (0.38) KDM4EOGTUSP2MAPTRECQL
SCHEMBL11100246 0.60 MIF (0.32) MIF
Water SCHEMBL864068 0.55 KDM4E (0.43) KDM4EOGTUSP2MAPTRECQL
SCHEMBL24066339 0.54
Alloxan SCHEMBL8924365 0.53 KDM4E (0.92) KDM4EOGTUSP2MAPTRECQL
Alloxan SCHEMBL9093366 0.53 KDM4E (0.92) KDM4EOGTUSP2MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0158921-A2 5-Imino-imidazolidinedione derivatives and process for the preparation of N,N'-disubstituted 5-imino-imidazolidinediones BAYER AG (DE) 1985-10-23 EP disclosed