SCHEMBL11310397

SCHEMBL11310397

NC(=O)N=C1NC(=O)NC1=O

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
OGT O15294 1/20 0.36
USP2 O75604 1/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11310393 1.00 KDM4E (0.36) KDM4EOGTUSP2MAPTRECQL
SCHEMBL10998274 0.77 KDM4E (0.36) KDM4EOGTUSP2MAPTRECQL
SCHEMBL10998271 0.77 KDM4E (0.36) KDM4EOGTUSP2MAPTRECQL
SCHEMBL10995850 0.70
SCHEMBL11860484 0.60 KDM4E (0.38) KDM4EOGTUSP2MAPTRECQL
SCHEMBL3279621 0.60 KDM4E (0.38) KDM4EOGTUSP2MAPTRECQL
SCHEMBL7401749 0.60 KDM4E (0.38) KDM4EOGTUSP2MAPTRECQL
Barbituric Acid SCHEMBL141571 0.60 ALDH1A1 (0.50) KDM4EOGTUSP2MAPTRECQL
Urea SCHEMBL28381632 0.56
Alloxan SCHEMBL64547 0.55 MAPT (1.00) KDM4EOGTUSP2MAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4345935-A PREEMERGENT AND POSTEMERGENT APPLICATION ELI LILLY AND COMPANY (US) 1982-08-24 US disclosed
US-4345936-A Imidazoles, compositions and herbicidal method ELI LILLY AND COMPANY (US) 1982-08-24 US disclosed