Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | FFAR2 | O15552 | 5/20 | 0.45 |
| ▸ | ACE | P12821 | 4/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090005 | 0.93 | KMT2A (0.61) | KMT2AFFAR2ACE | |
| SCHEMBL10995530 | 0.84 | ACE (0.46) | KMT2AFFAR2ACETERT | |
| SCHEMBL11191699 | 0.83 | ACE (0.47) | KMT2AFFAR2ACE | |
| SCHEMBL10824004 | 0.82 | KMT2A (0.46) | KMT2AFFAR2ACE | |
| SCHEMBL11247723 | 0.80 | KMT2A (0.66) | KMT2AFFAR2ACEMME | |
| SCHEMBL10998914 | 0.78 | ACE (0.48) | FFAR2ACETERTMME | |
| SCHEMBL11188897 | 0.77 | ACE (0.63) | FFAR2ACE | |
| SCHEMBL11092497 | 0.76 | KMT2A (0.43) | KMT2A | |
| SCHEMBL11097991 | 0.76 | KMT2A (0.43) | KMT2A | |
| SCHEMBL10938815 | 0.75 | ACE (0.71) | KMT2AFFAR2ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496578-A | Antihypertensive sulfur-containing compounds | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1985-01-29 | — | — | US | claimed |