Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7345254 | 0.98 | NPC1 (0.50) | NPC1KDM4EALDH1A1LMNAKLK1 | |
| SCHEMBL29707260 | 0.88 | CASR (0.56) | NPC1KDM4EALDH1A1LMNAMAPT | |
| Hydrochloric Acid SCHEMBL31436849 | 0.85 | CASR (0.53) | NPC1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL18550691 | 0.83 | ALDH1A1 (0.48) | NPC1KDM4EALDH1A1LMNANEU3 | |
| SCHEMBL141675 | 0.82 | NEU3 (0.60) | NPC1KDM4EALDH1A1NEU3MAPT | |
| Bicarbonate SCHEMBL17339675 | 0.81 | MEN1 (0.59) | NPC1ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL3586872 | 0.81 | NEU3 (0.58) | NPC1KDM4EALDH1A1LMNANEU3 | |
| Trifluoroacetic Acid SCHEMBL23246302 | 0.80 | CASR (0.49) | NPC1KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL7976228 | 0.80 | KLK1 (0.47) | NPC1KDM4EALDH1A1LMNAKLK1 | |
| SCHEMBL2348513 | 0.79 | KDM5A (0.57) | NPC1KDM4EALDH1A1NEU3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111278478-A | Kit for anchoring an implantable medical device | 美敦力公司 | 2020-06-12 | — | — | CN | disclosed |
| US-4532255-A | Amidine compounds and anticomplement agent comprising same | TORII & CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |