Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 4/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | XBP1 | P17861 | 1/20 | 0.65 |
| ▸ | CCR6 | P51684 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | MYOC | Q99972 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007631 | 0.89 | MEN1 (0.67) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11001115 | 0.89 | MEN1 (0.76) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11007212 | 0.87 | MEN1 (0.65) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11006538 | 0.86 | MEN1 (0.69) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL8104833 | 0.83 | P2RY1 (0.61) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4682789 | 0.83 | MEN1 (0.68) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4682794 | 0.83 | MEN1 (0.68) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11000732 | 0.80 | EPHX1 (0.69) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL4233557 | 0.79 | MEN1 (0.60) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL6940443 | 0.79 | MEN1 (0.62) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015110-B1 | ANTICOCCIDIAL COMPOSITION, CARBANILIDES AND METHOD OF PREPARING THEM | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |
| US-4526997-A | Amino, nitro, fluoro substituted carbanilides | DOHERTY GEORGE O P O | 1985-07-02 | — | — | US | disclosed |
| US-4468380-A | Anticoccidial combinations comprising polyether antibiotics and carbanilides | ELI LILLY AND COMPANY (US) | 1984-08-28 | — | — | US | disclosed |
| EP-0015110-A2 | Anticoccidial composition, carbanilides and method of preparing them | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | disclosed |