Pyridine

Pyridine

SCHEMBL11002811

CO.ClC(Cl)Cl.c1ccncc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.60
TSHR P16473 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL11341725 1.00 NAPRT (0.60) NAPRTTSHRTDP1SLC6A2SLC6A4
Pyridine SCHEMBL1333318 0.93 TSHR (0.69) NAPRTTSHRTDP1SLC6A2SLC6A4
Pyridine SCHEMBL6396742 0.93 TSHR (0.69) NAPRTTSHRTDP1SLC6A2SLC6A4
Pyridine SCHEMBL3908730 0.90 TSHR (0.64) NAPRTTSHRTDP1SLC6A2SLC6A4
Pyridine SCHEMBL8061420 0.90 TSHR (0.64) NAPRTTSHRTDP1SLC6A2SLC6A4
Pyridine SCHEMBL28351603 0.88 TSHR (0.53) NAPRTTSHRTDP1SMN1; SMN2
Pyridine SCHEMBL6515981 0.87 TSHR (0.60) NAPRTTSHRTDP1SLC6A2SLC6A4
Pyridine SCHEMBL2348132 0.86 NAPRT (0.82) NAPRTTSHRTDP1SLC6A2SLC6A4
Pyridine SCHEMBL15309118 0.86 NAPRT (0.82) NAPRTTSHRTDP1SLC6A2SLC6A4
Pyridine SCHEMBL1206485 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4349846-A1 CHIMERIC NUCLEIC ACID OLIGOMER INCLUDING PHOSPHOROTHIOATE AND BORANOPHOSPHATE, AND METHOD FOR PRODUCING SAME TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2024-04-10 EP disclosed
CN-117412983-A Chimeric nucleic acid oligomer comprising phosphorothioate and borazine phosphate, and method for producing same 学校法人东京理科大学 2024-01-16 CN disclosed
WO-2022255469-A1 CHIMERIC NUCLEIC ACID OLIGOMER INCLUDING PHOSPHOROTHIOATE AND BORANOPHOSPHATE, AND METHOD FOR PRODUCING SAME 学校法人東京理科大学 2022-12-08 WO disclosed
US-4525299-A (-)-15-Deoxyspergualin, process for the preparation thereof, and intermediate of the same ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1985-06-25 US disclosed
US-RE30496-E Tripeptide derivatives with central nervous system activity and preparation thereof AYERST, MCKENNA & HARRISON, LTD. (CA) 1981-01-27 US disclosed
US-4216209-A Tripeptide angiotensin converting enzyme inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 1980-08-05 US disclosed
US-4159980-A Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor AMERICAN HOME PRODUCTS CORPORATION (US) 1979-07-03 US disclosed
US-4093610-A CYCLIC DODECAPEPTIDE, MULTISTAGE AMERICAN HOME PRODUCTS CORPORATION (US) 1978-06-06 US disclosed
US-4018912-A Tripeptide derivatives with central nervous system activity and preparation thereof AYERST MCKENNA AND HARRISON LTD. (CA) 1977-04-19 US disclosed
US-3947569-A Process for preparing the releasing hormone of luteinizing hormone (LH) and of follicle stimulating hormone (FSH), salts and compositions thereof, and intermediates therefor AMERICAN HOME PRODUCTS CORPORATION (US) 1976-03-30 US disclosed