Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.64 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL6515981 | 0.97 | TSHR (0.60) | TSHRNAPRTTDP1GAASLC6A2 | |
| Pyridine SCHEMBL3747435 | 0.94 | TSHR (0.56) | TSHRNAPRTTDP1GAASLC6A2 | |
| Pyridine SCHEMBL28351603 | 0.91 | TSHR (0.53) | TSHRNAPRTTDP1GAA | |
| Pyridine SCHEMBL11341725 | 0.90 | NAPRT (0.60) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL11002811 | 0.90 | NAPRT (0.60) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL6396742 | 0.89 | TSHR (0.69) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL1333318 | 0.89 | TSHR (0.69) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| 1,1,2,2-Tetrachloroethane SCHEMBL11881109 | 0.86 | TDP1 (0.64) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL8061420 | 0.86 | TSHR (0.64) | TSHRNAPRTTDP1SLC6A2SLC6A4 | |
| Pyridine SCHEMBL547127 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556001-A2 | THERAPEUTIC COMPOSITIONS FOR DRUG DELIVERY TO AND THROUGH COVERING EPITHELIA | UMD, Inc. (US) | 2005-07-27 | — | — | EP | claimed |
| US-20040151774-A1 | Therapeutic compositions for drug delivery to and through covering epithelia | UMD, INC. | 2004-08-05 | — | — | US | claimed |
| WO-2004041118-A2 | THERAPEUTIC COMPOSITIONS FOR DRUG DELIVERY TO AND THROUGH COVERING EPITHELIA | UMD, INC. (US) | 2004-05-21 | — | — | WO | claimed |
| US-7524600-B2 | Electrophotographic toner | SHARP KABUSHIKI KAISHA (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20060177755-A1 | not undergoing the effect of change of temperature and humidity, with high charging stability and having good fixing property and releasability; polyester resin having an aromatic alcohol ingredient, the charge controller comprises an organic bentonite and the wax comprises a non-polar paraffin wax | SHARP KABUSHIKI KAISHA (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1556001-A2 | THERAPEUTIC COMPOSITIONS FOR DRUG DELIVERY TO AND THROUGH COVERING EPITHELIA | UMD, Inc. (US) | 2005-07-27 | — | — | EP | disclosed |
| US-20040151774-A1 | Therapeutic compositions for drug delivery to and through covering epithelia | UMD, INC. | 2004-08-05 | — | — | US | disclosed |
| WO-2004041118-A2 | THERAPEUTIC COMPOSITIONS FOR DRUG DELIVERY TO AND THROUGH COVERING EPITHELIA | UMD, INC. (US) | 2004-05-21 | — | — | WO | disclosed |