Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10955721 | 0.81 | KMT2A (0.32) | LMNACYP1A2CYP2C19KMT2A | |
| SCHEMBL10952766 | 0.73 | ADORA2A (0.31) | — | |
| SCHEMBL11441778 | 0.72 | LMNA (0.44) | LMNAL3MBTL1GAACYP1A2CYP2C19 | |
| SCHEMBL10987363 | 0.70 | LMNA (0.50) | LMNAL3MBTL1GAACYP1A2CYP2C19 | |
| SCHEMBL3265896 | 0.68 | LMNA (0.50) | LMNAL3MBTL1GAACYP1A2CYP2C19 | |
| SCHEMBL2772381 | 0.65 | LMNA (0.46) | LMNAL3MBTL1GAACYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL28599799 | 0.65 | LMNA (0.43) | LMNAL3MBTL1GAACYP1A2CYP2C19 | |
| SCHEMBL15904001 | 0.65 | PDE10A (0.41) | LMNA | |
| Simazine SCHEMBL4731210 | 0.63 | LMNA (0.91) | LMNAL3MBTL1GAACYP1A2CYP2C19 | |
| SCHEMBL1034033 | 0.62 | LMNA (0.74) | LMNAL3MBTL1GAACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0024260-B1 | PYRIMIDINE COMPOUNDS, THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AS ACTIVE COMPOUNDS AND INTERMEDIATES THEREOF | CIBA-GEIGY AG (CH) | 1985-05-22 | — | — | EP | claimed |