Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997437 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10997469 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10999222 | 0.83 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10996871 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10997446 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11004180 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11789908 | 0.76 | SMN1; SMN2 (0.79) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10997957 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10996874 | 0.75 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10997439 | 0.74 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517191-A | 1-Amino-1,8-naphthyridine compounds useful as bactericides | STERLING DRUG INC. (US) | 1985-05-14 | — | — | US | disclosed |