Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 16/20 | 0.61 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944258 | 1.00 | ACE (0.61) | ACEACE2 | |
| SCHEMBL7365884 | 0.92 | ACE (0.61) | ACEACE2 | |
| SCHEMBL7361792 | 0.92 | ACE (0.61) | ACEACE2 | |
| SCHEMBL11038053 | 0.87 | ACE (0.65) | ACEACE2 | |
| SCHEMBL11038051 | 0.87 | ACE (0.65) | ACEACE2 | |
| SCHEMBL10942007 | 0.85 | ACE (0.58) | ACEACE2 | |
| SCHEMBL7321808 | 0.83 | ACE (0.65) | ACEACE2 | |
| SCHEMBL7321819 | 0.83 | ACE (0.65) | ACEACE2 | |
| SCHEMBL10655570 | 0.81 | ACE (0.76) | ACEACE2 | |
| SCHEMBL10656703 | 0.81 | ACE (0.76) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558150-A | ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1985-12-10 | — | — | US | disclosed |
| US-4500518-A | ANALGESICS, HYPTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1985-02-19 | — | — | US | disclosed |