Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803276 | 0.95 | KDM4E (0.67) | KDM4EALDH1A1GAAMGAMAMY1A | |
| SCHEMBL8602349 | 0.95 | KDM4E (0.67) | KDM4EALDH1A1GAAMGAMAMY1A | |
| SCHEMBL11008645 | 0.94 | KDM4E (0.61) | KDM4EALDH1A1GAAMGAMAMY1A | |
| SCHEMBL11013048 | 0.93 | KDM4E (0.60) | KDM4EALDH1A1GAAMGAMAMY1A | |
| SCHEMBL11012241 | 0.92 | ALDH1A1 (0.53) | KDM4EALDH1A1GAAMGAMAMY1A | |
| SCHEMBL11007091 | 0.92 | KDM4E (0.52) | KDM4EALDH1A1GAANPSR1TP53 | |
| SCHEMBL11007569 | 0.92 | KDM4E (0.59) | KDM4EALDH1A1GAAMGAMAMY1A | |
| SCHEMBL11010459 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1GAAMGAMAMY1A | |
| SCHEMBL11008342 | 0.91 | KDM4E (0.58) | KDM4EALDH1A1GAAMGAMAMY1A | |
| SCHEMBL11011266 | 0.91 | ALDH1A1 (0.51) | KDM4EALDH1A1NPSR1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4532248-A | Administering 1,4-dihydropyridine derivative exhibiting positive inotropic activity | BAYER AKTIENGESELLSCHAFT (DE) | 1985-07-30 | — | — | US | disclosed |