Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 4/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | YARS1 | P54577 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10993025 | 1.00 | FOLH1 (0.46) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL5995942 | 0.99 | FOLH1 (0.47) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL5904162 | 0.99 | FOLH1 (0.47) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL2896479 | 0.99 | FOLH1 (0.47) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL6129097 | 0.99 | FOLH1 (0.47) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL8680647 | 0.87 | ATM (0.46) | NAALAD2ATMKMT2ACA1CA2 | |
| SCHEMBL10852869 | 0.87 | ATM (0.46) | NAALAD2ATMKMT2ACA1CA2 | |
| SCHEMBL9302331 | 0.87 | ATM (0.46) | NAALAD2ATMKMT2ACA1CA2 | |
| SCHEMBL11226776 | 0.86 | CA1 (0.40) | FOLH1NAALAD2KMT2ACA12CA1 | |
| SCHEMBL9302453 | 0.86 | CA1 (0.40) | FOLH1NAALAD2KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132394-A1 | Improvements in or relating to the preparation of 3-exomethylene cephalosporins | ELI LILLY AND COMPANY (US) | 1985-01-30 | — | — | EP | disclosed |