Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.47 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | YARS1 | P54577 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5904162 | 1.00 | FOLH1 (0.47) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL5995942 | 1.00 | FOLH1 (0.47) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL2896479 | 1.00 | FOLH1 (0.47) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL10993025 | 0.99 | FOLH1 (0.46) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL11005153 | 0.99 | FOLH1 (0.46) | FOLH1NAALAD2ATMKMT2ACA12 | |
| SCHEMBL8680647 | 0.88 | ATM (0.46) | NAALAD2ATMKMT2ACA1CA2 | |
| SCHEMBL10852869 | 0.88 | ATM (0.46) | NAALAD2ATMKMT2ACA1CA2 | |
| SCHEMBL9302331 | 0.88 | ATM (0.46) | NAALAD2ATMKMT2ACA1CA2 | |
| SCHEMBL11226776 | 0.87 | CA1 (0.40) | FOLH1NAALAD2KMT2ACA12CA1 | |
| SCHEMBL9302453 | 0.87 | CA1 (0.40) | FOLH1NAALAD2KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019345-B1 | PROCESS FOR THE PREPARATION OF A (D-ALPHA-AMINO-(P-HYDROXYPHENYL)-ACETAMIDO) GROUP CONTAINING CEPHALOSPORANIC ACID DERIVATIVES | GIST-BROCADES N.V. (NL) | 1985-06-19 | — | — | EP | claimed |
| EP-2213676-A1 | A Novel process for preparation of cefprozil | Hetero Drugs Limited (IN) | 2010-08-04 | — | — | EP | disclosed |
| EP-1809638-B1 | A NOVEL PROCESS FOR PREPARATION OF CEFPROZIL INTERMEDIATE | HETERO DRUGS LTD (IN) | 2010-02-17 | — | — | EP | disclosed |
| US-7629482-B2 | Process for preparation of cefprozil intermediate | HETERO DRUGS LIMITED (IN) | 2009-12-08 | — | — | US | disclosed |
| US-7629482-B2 | Process for preparation of cefprozil intermediate | HETERO DRUGS LIMITED (IN) | 2009-12-08 | — | — | US | disclosed |
| US-20090048460-A1 | NOVEL PROCESS FOR PREPARATION OF CEFPROZIL INTERMEDIATE | HETERO DRUGS LIMITED | 2009-02-19 | — | — | US | disclosed |
| US-20090048460-A1 | NOVEL PROCESS FOR PREPARATION OF CEFPROZIL INTERMEDIATE | HETERO DRUGS LIMITED | 2009-02-19 | — | — | US | disclosed |
| US-20080281093-A1 | Novel Process For Preparation of Cefprozil Intermediate | HETERO DRUGS LIMITED (IN) | 2008-11-13 | — | — | US | disclosed |
| US-20080281093-A1 | Novel Process For Preparation of Cefprozil Intermediate | HETERO DRUGS LIMITED (IN) | 2008-11-13 | — | — | US | disclosed |
| EP-1608661-A2 | PROCESS FOR THE PREPARATON OF 7-(P-HYDROXYPHENYLGLYCYLAMIDO)CEPHEM COMPOUNDS | Ranbaxy Laboratories Limited (IN) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004083172-A2 | PROCESS FOR THE PREPARATION OF 7-AMINO (P-HYDROXYPHENYLGLYCLYAMIDO) CEPHEM COMPOUNDS | RANBAXY LABORATORIES LIMITED (IN) | 2004-09-30 | — | — | WO | disclosed |
| US-4358588-A | 7-/D-ALPHA-AMINO/P-HYDROXYPHENYL/ACETAMIDO-3- CEPHEM-4-CARBOXYLIC ACID DERIVATIVES; EFFICIENCY | GIST-BROCADES N.V. (NL) | 1982-11-09 | — | — | US | disclosed |
| EP-0001133-B1 | PROCESS FOR THE PREPARATION OF 6- D-ALPHA-AMINO-(P-HYDROXYPHENYL)-ACETAMIDO PENICILLANIC ACID | GIST-BROCADES N.V. (NL) | 1982-01-20 | — | — | EP | disclosed |
| EP-0001133-A1 | Process for the preparation of 6- D-alpha-amino-(p-hydroxyphenyl)-acetamido penicillanic acid | GIST-BROCADES N.V. (NL) | 1979-03-21 | — | — | EP | disclosed |
| US-4128547-A | TERTIARY AMINE CATALYST | GIST-BROCADES N.V. (NL) | 1978-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080281093-A1 | Novel Process For Preparation of Cefprozil Intermediate | PTMA, PCMT1, CYP4Z1 | FOLH1 2010/4885NAALAD2 54/4885ATM 3369/4885 |
| US-20090048460-A1 | NOVEL PROCESS FOR PREPARATION OF CEFPROZIL INTERMEDIATE | PTMA, PCMT1, CYP4Z1 | FOLH1 2010/4885NAALAD2 54/4885ATM 3369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.