Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.66 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.66 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.57 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.51 |
| ▸ | TLR2 | O60603 | 3/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.48 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.48 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059626 | 0.88 | LPAR1 (0.59) | LPAR3LPAR1LPAR2LPAR5S1PR2 | |
| SCHEMBL8933348 | 0.88 | LPAR1 (0.59) | LPAR3LPAR1LPAR2LPAR5S1PR2 | |
| SCHEMBL1086081 | 0.83 | LPAR5 (0.65) | LPAR3LPAR1LPAR2LPAR5S1PR2 | |
| SCHEMBL1086079 | 0.83 | LPAR5 (0.65) | LPAR3LPAR1LPAR2LPAR5S1PR2 | |
| SCHEMBL19257792 | 0.81 | LPAR1 (0.59) | LPAR3LPAR1LPAR2LPAR5TLR2 | |
| Phosphoric Acid SCHEMBL9136512 | 0.81 | LPAR1 (0.69) | LPAR3LPAR1LPAR2LPAR5TLR2 | |
| Phosphoric Acid SCHEMBL9694084 | 0.80 | LPAR1 (0.59) | LPAR3LPAR1LPAR2LPAR5TLR2 | |
| SCHEMBL11004956 | 0.80 | PLCG2 (0.66) | LPAR3LPAR1LPAR2LPAR5PLCG2 | |
| SCHEMBL16475723 | 0.80 | LPAR1 (0.58) | LPAR3LPAR1LPAR2LPAR5TLR2 | |
| SCHEMBL11300983 | 0.80 | LPAR1 (0.58) | LPAR3LPAR1LPAR2LPAR5TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515722-A | Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents | MERCK & CO., INC. (US) | 1985-05-07 | — | — | US | disclosed |