Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.41 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 6/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154677 | 0.89 | LPAR1 (0.47) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Di(Hydroxyethyl)Ether SCHEMBL9128715 | 0.82 | TSHR (0.61) | LPAR1LPAR3LPAR2TLR2PLA2G2C | |
| SCHEMBL11069407 | 0.81 | TSHR (0.54) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL27240017 | 0.81 | LPAR1 (0.53) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL7723823 | 0.81 | LPAR1 (0.53) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL28332277 | 0.81 | LPAR1 (0.47) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL11005207 | 0.80 | LPAR3 (0.66) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL21060708 | 0.79 | LPAR1 (0.56) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| Phosphoric Acid SCHEMBL9136512 | 0.79 | LPAR1 (0.69) | LPAR1LPAR3LPAR2LPAR5LPAR6 | |
| SCHEMBL13884985 | 0.79 | PLA2G2C (0.48) | LPAR1LPAR3TLR2PLA2G2CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171478-A | Doping with organic acids or salts; electroconductive | ALLIED-SIGNAL INC. (US) | 1992-12-15 | — | — | US | disclosed |
| US-4094852-A | Process for the production of polytriazines in the presence of high-boiling esters | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-13 | — | — | US | disclosed |