Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.68 |
| ▸ | ALPG | P10696 | 1/20 | 0.67 |
| ▸ | PTAFR | P25105 | 4/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CASP1 | P29466 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11009173 | 0.86 | ALPG (0.71) | AKR1B1ALPGPTAFRTBXAS1KDM4E | |
| SCHEMBL11034933 | 0.82 | ALPG (0.51) | AKR1B1ALPGPTAFRTBXAS1KDM4E | |
| SCHEMBL11007275 | 0.82 | AKR1B1 (0.82) | AKR1B1ALPGPTAFRTBXAS1KDM4E | |
| SCHEMBL11269862 | 0.81 | ALPG (0.64) | AKR1B1ALPGPTAFRTBXAS1KDM4E | |
| SCHEMBL11276137 | 0.81 | ALPG (0.67) | AKR1B1ALPGPTAFRTBXAS1KDM4E | |
| SCHEMBL11009207 | 0.81 | ALPG (0.67) | AKR1B1ALPGPTAFRTBXAS1 | |
| SCHEMBL11002651 | 0.81 | ALPG (1.00) | AKR1B1ALPGPTAFRTBXAS1KDM4E | |
| SCHEMBL11270745 | 0.81 | ALPG (0.67) | AKR1B1ALPGPTAFRTBXAS1KDM4E | |
| SCHEMBL11203945 | 0.81 | ALPG (0.54) | AKR1B1ALPGPTAFRTBXAS1KDM4E | |
| SCHEMBL11245977 | 0.80 | AKR1B1 (0.71) | AKR1B1ALPGPTAFRTBXAS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4551460-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1985-11-05 | — | — | US | disclosed |