Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10882986 | 0.89 | KMT2A (0.58) | KMT2AALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL11001002 | 0.83 | KMT2A (0.63) | KMT2AALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL9833601 | 0.77 | KMT2A (0.47) | KMT2AALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL9834872 | 0.77 | KMT2A (0.47) | KMT2AALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL10391870 | 0.76 | ALDH1A1 (0.68) | KMT2AALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL9007847 | 0.74 | ALDH1A1 (0.68) | KMT2AALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL10550406 | 0.73 | ALDH1A1 (0.60) | KMT2AALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL11006464 | 0.73 | ALDH1A1 (0.57) | KMT2AALDH1A1CYP3A4MEN1LMNA | |
| SCHEMBL20030387 | 0.72 | KMT2A (0.65) | KMT2AALDH1A1CYP3A4LMNACYP1A2 | |
| SCHEMBL9662635 | 0.71 | KMT2A (1.00) | KMT2AALDH1A1SMN1; SMN2CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150036-A1 | Azolyl-aryl-alkanole-derivatives, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-31 | — | — | EP | claimed |