SCHEMBL11005283

SCHEMBL11005283

Oc1ccc2c(c1)OC(c1ccccc1)(c1ccccc1)O2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 11/20 0.49
CYP3A4 P08684 1/20 0.39
SRD5A1 P18405 1/20 0.38
SRD5A2 P31213 1/20 0.38
HPGD P15428 2/20 0.37
MEN1 O00255 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C19 P33261 1/20 0.37
HTT P42858 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
SMAD3 P84022 1/20 0.37
KMT2A Q03164 1/20 0.37
PRMT1 Q99873 1/20 0.37
ACE2 Q9BYF1 1/20 0.37
FTO Q9C0B1 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
HSP90AA1 P07900 1/20 0.37
ALDH1A1 P00352 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11005292 0.81 SIRT1 (0.49) CNR1CYP3A4HPGDMEN1MAPT
SCHEMBL7442888 0.79 CNR1 (0.44) CNR1SRD5A1SRD5A2MEN1MAPT
SCHEMBL30307890 0.79 CNR1 (0.44) CNR1SRD5A1SRD5A2MEN1MAPT
SCHEMBL6485133 0.77 AHR (0.48) CNR1SRD5A1SRD5A2MAPTHTT
SCHEMBL763027 0.77 CNR1 (0.46) CNR1SRD5A1SRD5A2TDP1
SCHEMBL4464683 0.77 MAPT (0.49) CNR1CYP3A4SRD5A1SRD5A2HPGD
SCHEMBL30257325 0.77 CNR1 (0.63) CNR1SRD5A1SRD5A2ALDH1A1HSD17B10
SCHEMBL8728950 0.77 CNR1 (0.63) CNR1SRD5A1SRD5A2ALDH1A1HSD17B10
SCHEMBL9142026 0.77 CNR1 (0.46) CNR1SRD5A1SRD5A2ALOX15ALOX12
SCHEMBL9040996 0.75 CNR1 (0.62) CNR1SRD5A1SRD5A2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-7314693-B2 Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2008-01-01 US disclosed
US-4499115-A FOR FOODS UNISEARCH LIMITED (AU) 1985-02-12 US disclosed