Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20738450 | 1.00 | ACHE (0.46) | ACHEACP3EPHX1TP53TDP1 | |
| SCHEMBL29378635 | 0.86 | ACHE (0.55) | ACHEACP3EPHX1TP53TDP1 | |
| SCHEMBL931982 | 0.86 | ACHE (0.55) | ACHEACP3EPHX1TP53TDP1 | |
| SCHEMBL16571477 | 0.83 | ACHE (0.46) | ACHEACP3EPHX1TP53TDP1 | |
| SCHEMBL14087826 | 0.82 | ACHE (0.50) | ACHEACP3EPHX1TP53TDP1 | |
| SCHEMBL3071260 | 0.82 | ACHE (0.50) | ACHEACP3EPHX1TP53TDP1 | |
| SCHEMBL343187 | 0.82 | ACHE (0.50) | ACHEACP3EPHX1TP53TDP1 | |
| SCHEMBL429838 | 0.82 | ACHE (0.50) | ACHEACP3EPHX1TP53TDP1 | |
| SCHEMBL16956849 | 0.81 | ACP3 (0.44) | ACHEACP3EPHX1TP53TDP1 | |
| SCHEMBL6055386 | 0.80 | ACHE (0.48) | ACHEACP3EPHX1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0149976-A2 | Substituted imidazoles | CIBA-GEIGY AG (CH) | 1985-07-31 | — | — | EP | disclosed |