Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.57 |
| ▸ | LMNA | P02545 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7279962 | 0.89 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL7432721 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL11421509 | 0.82 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL3952909 | 0.80 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL25620098 | 0.78 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL29286736 | 0.78 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL10603992 | 0.77 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL11232605 | 0.76 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL307790 | 0.76 | MEN1 (0.62) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 | |
| SCHEMBL28678015 | 0.76 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2LMNAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4510140-A | HYPOTENSIVE AGENTS; ANTHIHISTAMINES; ANALGESICS; SEDATIVES | RECORDATI S.A. (CH) | 1985-04-09 | — | — | US | disclosed |
| EP-0074768-A2 | Alkanoylanilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1983-03-23 | — | — | EP | disclosed |