Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK2 | Q13002 | 3/20 | 0.61 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12352758 | 0.86 | NPSR1 (0.64) | GRIK2GRIK1TDP1SMN1; SMN2NPSR1 | |
| SCHEMBL31121588 | 0.84 | KDM4E (0.64) | GRIK2GRIK1TDP1SMN1; SMN2MAPT | |
| SCHEMBL11682381 | 0.84 | KDM4E (0.64) | GRIK2GRIK1TDP1SMN1; SMN2MAPT | |
| SCHEMBL27204181 | 0.80 | GRIK1 (0.45) | GRIK2GRIK1TDP1PTGER4AKR1C3 | |
| SCHEMBL1436061 | 0.80 | HTR2C (0.61) | GRIK2GRIK1TDP1AKR1C3AKR1C2 | |
| SCHEMBL4465081 | 0.79 | MAPT (0.57) | GRIK2GRIK1TDP1SMN1; SMN2MAPT | |
| SCHEMBL6717869 | 0.79 | MAPT (0.55) | TDP1SMN1; SMN2MAPTKDM4EAKR1C3 | |
| SCHEMBL6085520 | 0.79 | CCR2 (0.56) | MAPTKDM4EAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL9581147 | 0.78 | KMT2A (0.47) | GRIK2GRIK1TDP1SMN1; SMN2NPSR1 | |
| SCHEMBL23927884 | 0.77 | HTR2C (0.45) | GRIK2GRIK1TDP1KDM4EAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525588-A | FOR HEAT AND PRESSURE SENSITIVE RECORDING MATERIALS | CIBA GEIGY CORPORATION (US) | 1985-06-25 | — | — | US | disclosed |
| US-4465761-A | HALO COMPOUND, LEUCO DYE, AROMATIC AMINE SENSITIZER, BINDER AND ALIPHATIC AMINE; ANTIFOGGING AGENTS | ORIENTAL PHOTO INDUSTRIES CO., LTD. (JP) | 1984-08-14 | — | — | US | disclosed |
| EP-0026859-B1 | IMAGE-FORMING PHOTOSENSITIVE COMPOSITION, PHOTOSENSITIVE COATING SOLUTION AND PHOTOSENSITIVE SHEET COMPRISING THIS COMPOSITION | ORIENTAL PHOTO INDUSTRIES, CO., LTD. (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4102893-A | Process for the manufacture of color formers of indoles and anhydrides of aromatic or heteroaromatic, vicinal dicarboxylic acids, new color formers of these classes of substance and their use | CIBA-GEIGY AG (CH) | 1978-07-25 | — | — | US | disclosed |
| US-3969346-A | Naphtholactamcarbinols color formers, their manufacture and use in pressure-sensitive or thermoreactive recording material | CIBA-GEIGY CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |