Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 0.68 |
| ▸ | PGR | P06401 | 3/20 | 0.68 |
| ▸ | PPARG | P37231 | 2/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.59 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 10/20 | 0.59 |
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939443 | 0.89 | NR1I2 (0.70) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL10939435 | 0.89 | NR1I2 (0.70) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11004976 | 0.88 | NR1I2 (0.88) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11004971 | 0.88 | NR1I2 (0.88) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11040788 | 0.86 | NR1I2 (0.64) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11040786 | 0.86 | NR1I2 (0.64) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11010981 | 0.86 | NR1I2 (0.71) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11010966 | 0.86 | NR1I2 (0.71) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9659942 | 0.85 | NR1I2 (0.61) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL9659935 | 0.85 | NR1I2 (0.61) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503221-A | PYRAZOLYL OXIME AMIDE | SANDOZ LTD. (CH) | 1985-03-05 | — | — | US | disclosed |
| US-4440767-A | Derivatives of cephalosporanic acid, processes for their production and their use | SANDOZ LTD. (CH) | 1984-04-03 | — | — | US | disclosed |