Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.57 |
| ▸ | SLC22A11 | Q9NSA0 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SPOP | O43791 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040788 | 1.00 | NR1I2 (0.64) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11048027 | 0.92 | NR1I2 (0.60) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11048025 | 0.92 | NR1I2 (0.60) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10939435 | 0.89 | NR1I2 (0.70) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10939443 | 0.89 | NR1I2 (0.70) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11044055 | 0.86 | NR1I2 (0.48) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11044052 | 0.86 | NR1I2 (0.48) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11005869 | 0.86 | NR1I2 (0.68) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11004976 | 0.85 | NR1I2 (0.88) | NR1I2PGRSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11004971 | 0.85 | NR1I2 (0.88) | NR1I2PGRSLC22A6SLC22A8SLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463003-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | claimed |
| US-4463003-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |