Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.72 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | SOD1 | P00441 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28742405 | 0.91 | CYP19A1 (0.68) | CYP19A1HMOX1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL8865557 | 0.84 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| Bromide SCHEMBL27949879 | 0.83 | CYP19A1 (0.97) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| Bromide SCHEMBL27949880 | 0.83 | CYP19A1 (0.97) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL409741 | 0.80 | HMOX1 (0.72) | CYP19A1HMOX1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL14416017 | 0.79 | CYP19A1 (0.60) | CYP19A1SOD1 | |
| SCHEMBL10923017 | 0.79 | POLB (0.62) | CYP19A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7527357 | 0.78 | HMOX1 (0.70) | CYP19A1HMOX1CYP11B1CYP11B2TBXAS1 | |
| Bromide SCHEMBL29223796 | 0.78 | HMOX1 (0.70) | CYP19A1HMOX1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL7737870 | 0.78 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104968712-B | Nested supermolecule capsule | 剑桥实业有限公司 | 2017-06-09 | — | — | CN | disclosed |
| US-4528195-A | Imidazole derivatives and salts thereof, their synthesis and intermediates and pharmaceutical formulations | THOROGOOD PETER B (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4416895-A | ANTICOAGULANTS, ANTISHOCK AGENTS | BURROUGHS WELLCOME CO. (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |