Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | PPOX | P50336 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004154 | 0.95 | TDP1 (0.59) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11009144 | 0.94 | TDP1 (0.58) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11004065 | 0.94 | MEN1 (0.58) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11005418 | 0.94 | TDP1 (0.60) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11003844 | 0.91 | TDP1 (0.62) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11006605 | 0.89 | TDP1 (0.60) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11007247 | 0.88 | TDP1 (0.65) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11106213 | 0.87 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9347451 | 0.84 | TDP1 (0.68) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL2233678 | 0.83 | TDP1 (0.73) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556413-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1985-12-03 | — | — | US | claimed |
| EP-0109575-A2 | Benzoic-acid derivatives, process and means for its production | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-05-30 | — | — | EP | claimed |
| US-4556413-A | POSTEMERGENCE AND PREEMERGENCE HERBICIDES | HOFFMANN-LA ROCHE INC. (US) | 1985-12-03 | — | — | US | disclosed |
| EP-0109575-A2 | Benzoic-acid derivatives, process and means for its production | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-05-30 | — | — | EP | disclosed |