Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.51 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908918 | 0.83 | POLB (0.81) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL1509681 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| Iodide SCHEMBL28192688 | 0.79 | CYP11B1 (0.97) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| Hydrochloric Acid SCHEMBL28135987 | 0.79 | CYP11B1 (0.97) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL10417519 | 0.78 | CYP19A1 (1.00) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL8866026 | 0.78 | POLB (1.00) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL30523908 | 0.77 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL30523909 | 0.77 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL15179016 | 0.77 | CYP11B1 (0.76) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| Hydrochloric Acid SCHEMBL1508037 | 0.77 | CYP19A1 (0.97) | CYP11B1CYP11B2CYP19A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528195-A | Imidazole derivatives and salts thereof, their synthesis and intermediates and pharmaceutical formulations | THOROGOOD PETER B (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4416895-A | ANTICOAGULANTS, ANTISHOCK AGENTS | BURROUGHS WELLCOME CO. (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |