SCHEMBL1509681

SCHEMBL1509681

Cc1ccccc1Cn1ccnc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 10/20 1.00
CYP11B2 P19099 9/20 1.00
CYP19A1 P11511 7/20 0.61
POLB P06746 2/20 0.61
TBXAS1 P24557 4/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2D6 P10635 1/20 0.58
MAPT P10636 1/20 0.58
QPCT Q16769 1/20 0.58
CYP4Z1 Q86W10 1/20 0.58
QPCTL Q9NXS2 1/20 0.58
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
CYP17A1 P05093 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28135987 0.98 CYP11B1 (0.97) CYP11B1CYP11B2CYP19A1POLBTBXAS1
Iodide SCHEMBL28192688 0.98 CYP11B1 (0.97) CYP11B1CYP11B2CYP19A1POLBTBXAS1
SCHEMBL30523909 0.87 CYP11B1 (0.76) CYP11B1CYP11B2CYP19A1POLBTBXAS1
SCHEMBL15179016 0.87 CYP11B1 (0.76) CYP11B1CYP11B2CYP19A1POLBTBXAS1
SCHEMBL30523908 0.87 CYP11B1 (0.76) CYP11B1CYP11B2CYP19A1POLBTBXAS1
SCHEMBL2776942 0.86 CYP11B1 (0.76) CYP11B1CYP11B2CYP19A1POLBTBXAS1
SCHEMBL6992090 0.83 CYP11B1 (0.71) CYP11B1CYP11B2CYP19A1TBXAS1MEN1
SCHEMBL17450431 0.82 CYP11B1 (0.70) CYP11B1CYP11B2CYP19A1POLBTBXAS1
SCHEMBL11620329 0.82 CYP11B1 (0.68) CYP11B1CYP11B2CYP19A1POLBTBXAS1
SCHEMBL15373316 0.81 CYP11B1 (0.68) CYP11B1CYP11B2CYP19A1POLBTBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114072444-B Curable composition, cured product, overcoat film, flexible wiring board, and method for producing same 日保丽公司 2024-07-09 CN disclosed
WO-2023274257-A1 IMIDAZOLE COMPOUND, AND INTERMEDIATE AND APPLICATION THEREOF 诸葛国琴 2023-01-05 WO disclosed
CN-107873015-B Crystal germanosilicate material with novel CIT-13 topological structure and preparation method thereof 加州理工学院 2021-12-24 CN disclosed
US-10828625-B2 Crystalline germanosilicate materials of new CIT-13 topology and methods of preparing the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2020-11-10 US disclosed
US-10717071-B2 Crystalline germanosilicate materials of new CIT-13 topology and methods of preparing the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2020-07-21 US disclosed
US-20190247835-A1 Crystalline Germanosilicate Materials Of New CIT-13 Topology And Methods Of Preparing The Same CALIFORNIA INSTITUTE OF TECHNOLOGY 2019-08-15 US disclosed
US-10293330-B2 Crystalline germanosilicate materials of new CIT-13 topology and methods of preparing the same CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2019-05-21 US disclosed
US-20190083962-A1 Crystalline Germanosilicate Materials Of New CIT-13 Topology And Methods Of Preparing The Same CALIFORNIA INSTITUTE OF TECHNOLOGY 2019-03-21 US disclosed
EP-3169662-B1 SUBSTITUTED VINYL- AND ALKINYL-CYANOCYCLOALKANOLS AND VINYL- AND ALKINYL-CYANOHETEROCYCLOALKANOLS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2018-07-11 EP disclosed
EP-3303221-A1 CRYSTALLINE GERMANOSILICATE MATERIALS OF NEW CIT-13 TOPOLOGY AND METHODS OF PREPARING THE SAME CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2018-04-11 EP disclosed
US-20060189523-A1 Use of effectors of glutaminyl and glutamate cyclases PROBIODRUG AG (DE) 2006-08-24 US disclosed
EP-1675578-A2 USE OF EFFECTORS OF GLUTAMINYL AND GLUTAMATE CYCLASES Probiodrug AG (DE) 2006-07-05 EP disclosed
EP-1622870-A2 GLUTAMINYL BASED DP IV-INHIBITORS Prosidion Ltd. (GB) 2006-02-08 EP disclosed
EP-1620082-A2 MEDICAL USE OF INHIBITORS OF GLUTAMINYL AND GLUTAMATE CYCLASES Probiodrug AG (DE) 2006-02-01 EP disclosed
EP-1620091-A2 INHIBITORS OF GLUTAMINYL CYCLASE Probiodrug AG (DE) 2006-02-01 EP disclosed
WO-2005039548-A2 USE OF EFFECTORS OF GLUTAMINYL AND GLUTAMATE CYCLASES PROBIODRUG AG (DE) 2005-05-06 WO disclosed
US-20050058635-A1 Anticancer agents; therapy for infections; administering glutaminyl cyclase inhibitor; Alzheimer's disease; Down syndrome; controlling fertility; schizophrenia; skin disorders PROBIODRUG AG (DE) 2005-03-17 US disclosed
WO-2004098591-A2 INHIBITORS OF GLUTAMINYL CYCLASE AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISEASES PROBIODRUG AG (DE) 2004-11-18 WO disclosed
WO-2004098625-A2 MEDICAL USE OF INHIBITORS OF GLUTAMINYL AND GLUTAMATE CYCLASES PROBIODRUG AG (DE) 2004-11-18 WO disclosed
WO-2004099134-A2 GLUTAMINYL BASED DP IV-INHIBITORS PROSIDION LTD. (GB) 2004-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10717071-B2 Crystalline germanosilicate materials of new CIT-13 topology and methods of preparing the same ATG13, CIT, MICOS13 CYP11B1 3779/4885CYP11B2 4147/4885CYP19A1 4036/4885
US-20060189523-A1 Use of effectors of glutaminyl and glutamate cyclases GLS, GLUL, GLS2 CYP11B1 2572/4885CYP11B2 2600/4885CYP19A1 3760/4885
US-10293330-B2 Crystalline germanosilicate materials of new CIT-13 topology and methods of preparing the same ATG13, SLC13A3, MICOS13 CYP11B1 3672/4885CYP11B2 4169/4885CYP19A1 4348/4885
US-20050058635-A1 Anticancer agents; therapy for infections; administering glutaminyl cyclase inhibitor; Alzheimer's disease; Down syndrome; controlling fertility; schizophrenia; skin disorders GLS, QPCT, GLS2 CYP11B1 2857/4885CYP11B2 2960/4885CYP19A1 827/4885
US-20190083962-A1 Crystalline Germanosilicate Materials Of New CIT-13 Topology And Methods Of Preparing The Same ATG13, CIT, MICOS13 CYP11B1 3779/4885CYP11B2 4147/4885CYP19A1 4036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.