SCHEMBL11007221

SCHEMBL11007221

CCCC(C)=CCC(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GGPS1 O95749 11/20 0.33
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11158723 0.80
SCHEMBL23379962 0.76 GGPS1 (0.33) GGPS1KMT2A
SCHEMBL11049806 0.76 LSS (0.42) GGPS1KMT2A
SCHEMBL11399041 0.75 ALDH1A1 (0.32)
SCHEMBL11399042 0.75 ALDH1A1 (0.32)
SCHEMBL16160760 0.72
SCHEMBL24661206 0.72
SCHEMBL13315591 0.72
SCHEMBL7943440 0.71 GGPS1 (0.35) GGPS1KMT2A
SCHEMBL9651787 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0003666-B1 OXABICYCLO 3.1.0 HEXANES USEFUL IN THE PRODUCTION OF CYCLOPROPANECARBOXYLATE INSECTICIDES AND INTERMEDIATE COMPOUNDS FMC Corporation (US) 1983-04-06 EP claimed
EP-0003666-A1 Oxabicyclo 3.1.0 hexanes useful in the production of cyclopropanecarboxylate insecticides and intermediate compounds FMC Corporation (US) 1979-08-22 EP claimed
US-4526987-A Alkyl 6,6-dimethyl-2-oxo-3-oxabicyclo[3.1.0]hexane-1-carboxylates FMC CORPORATION (US) 1985-07-02 US disclosed
EP-0003666-B1 OXABICYCLO 3.1.0 HEXANES USEFUL IN THE PRODUCTION OF CYCLOPROPANECARBOXYLATE INSECTICIDES AND INTERMEDIATE COMPOUNDS FMC Corporation (US) 1983-04-06 EP disclosed
US-4283341-A Process to bicyclic lactones FMC CORPORATION (US) 1981-08-11 US disclosed
US-4254282-A Process for preparing cis-3-(2,2-dihalovinyl)-2,2-dimethylcyclopropanecarboxylic acid FMC CORPORATION (US) 1981-03-03 US disclosed
EP-0003666-A1 Oxabicyclo 3.1.0 hexanes useful in the production of cyclopropanecarboxylate insecticides and intermediate compounds FMC Corporation (US) 1979-08-22 EP disclosed