Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 4/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10633347 | 0.91 | CTSL (0.53) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL10443977 | 0.91 | CTSL (0.57) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL1661198 | 0.89 | CTSL (0.57) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL27343926 | 0.89 | CTSL (0.54) | CTSLCAPN1TACR1CTSBCTSS | |
| SCHEMBL9551368 | 0.89 | CTSL (0.54) | CTSLCAPN1TACR1CTSBCTSS | |
| SCHEMBL27343932 | 0.89 | CTSL (0.54) | CTSLCAPN1TACR1CTSBCTSS | |
| SCHEMBL9551274 | 0.89 | CTSL (0.54) | CTSLCAPN1TACR1CTSBCTSS | |
| SCHEMBL9666956 | 0.89 | CTSL (0.54) | CTSLCAPN1TACR1CTSBCTSS | |
| SCHEMBL10982059 | 0.87 | CTSL (0.50) | CTSLTACR1CTSBCTSSCTSK | |
| SCHEMBL7264470 | 0.86 | TACR1 (0.51) | CTSLTACR1CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0143746-A2 | 5-Amino 4-hydroxy-valeryl-substituted derivatives | CIBA-GEIGY AG (CH) | 1985-06-05 | — | — | EP | disclosed |